An experimental study was conducted to examine the interaction between a single weak streamwise vortex and a two-dimensional turbulent boundary layer. Attention was focused on characterizing the effect of the boundary layer on the vortex, including the effects of a moderate adverse pressure gradient. Rapid growth of the vortex core was observed, and a flattening of the core shape occurred when the dimension of the core radius became comparable to the distance of the vortex center from the surface. Adverse pressure gradients caused an increase in the rate of core growth, and therefore, a stronger distortion of the core shape. Measurements of surface skin friction beneath the vortex and some of the Reynolds stresses are presented.