ESDU 86025 provides guidance on design of aerospace structures to avoid acoustically or similarly induced fatigue failure. The sources of excitation in an aerospace environment are reviewed. Modes of response and associated types of failure under a fluctuating pressure loading are considered and good detail design practice for typical aerospace structural elements is illustrated. Examples, based on actual case studies, of the use of good detail design to improve structural life are included. Also discussed is the design of the support structure when mounting systems and equipment in a high noise environment, again illustrated by a variety of examples of good and bad practice.